Sugi Predict

Sugi Predict / Compounds / SCHEMBL16450367

SCHEMBL16450367

SCHEMBL16450367

C#CCCCCOc1cc(C=O)cc(OCCCCC#C)c1OCCCCC#C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 3/20 0.39
▸ FDPS P14324 1/20 0.38
▸ MAOB P27338 4/20 0.37
▸ MAOA P21397 3/20 0.37
▸ ALDH1A1 P00352 6/20 0.36
▸ MAPT P10636 6/20 0.36
▸ SMN1; SMN2 Q16637 4/20 0.34
▸ HPGD P15428 3/20 0.34
▸ ATM Q13315 1/20 0.34
▸ LMNA P02545 4/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ HTT P42858 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16450540 0.98 ALOX5 (0.38) ALOX5FDPSMAOBMAOAALDH1A1
SCHEMBL16450742 0.90 MAOA (0.41) ALOX5FDPSMAOBMAOAALDH1A1
SCHEMBL16450741 0.87 ALOX5 (0.36) ALOX5FDPSMAOBMAOAALDH1A1
SCHEMBL16450580 0.82 MAOA (0.41) ALOX5FDPSMAOBMAOAALDH1A1
SCHEMBL17996853 0.80 ALOX5 (0.35) ALOX5FDPSMAOBMAOAALDH1A1
SCHEMBL16450342 0.80 MAOB (0.35) ALOX5FDPSMAOBMAOAALDH1A1
SCHEMBL16272285 0.79 FDPS (0.48) ALOX5FDPSMAOBMAOAALDH1A1
SCHEMBL16450337 0.79 MAOB (0.34) ALOX5FDPSMAOBMAOAALDH1A1
SCHEMBL1200827 0.78 FDPS (0.45) FDPSALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL27427150 0.78 FDPS (0.41) FDPSALDH1A1MAPTSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11578093-B2 Protected fluorescent reagent compounds PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-02-14 — — US disclosed
US-10787573-B2 Multimeric protected fluorescent reagents PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2020-09-29 — — US disclosed
WO-2016126941-A1 MULTIMERIC PROTECTED FLUORESCENT REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-08-11 — — WO disclosed
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2015-02-19 — — US disclosed
WO-2015021079-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2015-02-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS ERCC4, ERCC2, ERCC1 ALOX5 1644/4885FDPS 1689/4885MAOB 2047/4885
US-11578093-B2 Protected fluorescent reagent compounds ERCC4, ERCC2, ERCC1 ALOX5 1644/4885FDPS 1689/4885MAOB 2047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.