Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026113 | 0.81 | PTGS1 (0.31) | PTGS1SLC7A11MAPTKDM4ETHRB | |
| SCHEMBL28651642 | 0.78 | SLC1A3 (0.36) | PTGS1MAPTALDH1A1RNPEP | |
| SCHEMBL2631146 | 0.76 | CA2 (0.41) | PTGS1MAPTBLMALDH1A1 | |
| SCHEMBL667279 | 0.76 | OR51E2 (0.39) | PTGS1MAPTALDH1A1 | |
| SCHEMBL13316605 | 0.76 | OR51E2 (0.39) | PTGS1MAPTALDH1A1 | |
| SCHEMBL12891264 | 0.76 | CA2 (0.41) | PTGS1MAPTBLMALDH1A1 | |
| SCHEMBL276534 | 0.76 | CA2 (0.41) | PTGS1MAPTBLMALDH1A1 | |
| SCHEMBL10501109 | 0.75 | CYP3A4 (0.31) | NFKB1 | |
| SCHEMBL4874581 | 0.75 | PTGS1 (0.37) | PTGS1SLC7A11MAPTKDM4ETHRB | |
| SCHEMBL636537 | 0.74 | GABRR1 (0.37) | PTGS1MAPTKDM4EALDH1A1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104353-A1 | LIGAND-TARGETED MOLECULES AND METHODS THEREOF | INVICTUS ONCOLOGY PVT. LTD. (IN) | 2018-04-19 | — | — | US | disclosed |
| US-9884123-B2 | Ligand-targeted molecules and methods thereof | INVICTUS ONCOLOGY PVT. LTD. (IN) | 2018-02-06 | — | — | US | disclosed |
| US-20150045428-A1 | LIGAND-TARGETED MOLECULES AND METHODS THEREOF | INVICTUS ONCOLOGY PVT. LTD. (IN) | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104353-A1 | LIGAND-TARGETED MOLECULES AND METHODS THEREOF | HLCS, PAICS, CLTC | PTGS1 1526/4885SLC7A11 275/4885MAPT 3225/4885 |
| US-20150045428-A1 | LIGAND-TARGETED MOLECULES AND METHODS THEREOF | HLCS, PAICS, CLTC | PTGS1 1878/4885SLC7A11 314/4885MAPT 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.