Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16450754 | 0.85 | SMN1; SMN2 (0.52) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL20392776 | 0.84 | CA12 (0.56) | LMNAMAPK1NR1H4 | |
| SCHEMBL16450475 | 0.84 | LMNA (0.56) | ALDH1A1LMNAMEN1KMT2ARXFP1 | |
| SCHEMBL16491008 | 0.83 | LMNA (0.57) | ALDH1A1HPGDPLK1LMNAMEN1 | |
| SCHEMBL1004083 | 0.78 | RXFP1 (0.68) | ALDH1A1HPGDPLK1LMNAMEN1 | |
| SCHEMBL9903880 | 0.78 | PKM (0.62) | ALDH1A1HPGDPLK1LMNAMEN1 | |
| SCHEMBL4143482 | 0.78 | ALDH1A1 (0.77) | ALDH1A1HPGDPLK1LMNAMEN1 | |
| SCHEMBL31650388 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HPGDPLK1LMNAMEN1 | |
| SCHEMBL3808045 | 0.76 | CYP3A4 (0.50) | — | |
| SCHEMBL20392703 | 0.75 | LMNA (0.67) | ALDH1A1HPGDPLK1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017087975-A9 | LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-07-19 | — | — | WO | disclosed |
| WO-2015021079-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-02-12 | — | — | WO | disclosed |