Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.36 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.34 |
| ▸ | TERF2 | Q15554 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1655875 | 0.89 | BIRC3 (0.38) | F2F10PRSS1HDAC4HDAC1 | |
| SCHEMBL4295086 | 0.84 | ADRB3 (0.31) | F2F10PRSS1GAA | |
| SCHEMBL12343884 | 0.83 | F2 (0.33) | F2F10PRSS1GAAPLG | |
| SCHEMBL1685577 | 0.81 | GAA (0.34) | MEN1ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL14031132 | 0.80 | GAA (0.35) | F2F10PRSS1ALDH1A1GAA | |
| SCHEMBL8054841 | 0.80 | MEN1 (0.31) | F2F10PRSS1MEN1ALDH1A1 | |
| SCHEMBL6382019 | 0.79 | F2 (0.37) | F2F10PRSS1HDAC4HDAC1 | |
| SCHEMBL8249384 | 0.79 | F2 (0.37) | F2F10PRSS1HDAC4HDAC1 | |
| SCHEMBL1683122 | 0.79 | ADRB3 (0.36) | F2F10PRSS1XIAPBIRC3 | |
| SCHEMBL1645088 | 0.79 | ADRB3 (0.36) | F2F10PRSS1XIAPBIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305696-A2 | Macrocyclic inhibitors of Hepatitis C virus replication | Intermune, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |