Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 2/20 | 0.36 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8249384 | 1.00 | F2 (0.37) | F2F10PRSS1XIAPBIRC3 | |
| SCHEMBL1655875 | 0.85 | BIRC3 (0.38) | F2F10PRSS1XIAPBIRC3 | |
| SCHEMBL8239491 | 0.84 | BACE1 (0.33) | F2F10PRSS1GAA | |
| SCHEMBL19869647 | 0.84 | HDAC4 (0.38) | XIAPBIRC3BIRC2GAAHDAC4 | |
| SCHEMBL7919172 | 0.82 | BIRC3 (0.39) | XIAPBIRC3BIRC2HDAC4HDAC1 | |
| SCHEMBL13886148 | 0.80 | REN (0.33) | — | |
| SCHEMBL8278256 | 0.80 | REN (0.33) | — | |
| SCHEMBL8378473 | 0.80 | ADRB3 (0.42) | F2F10PRSS1XIAPBIRC3 | |
| SCHEMBL1645865 | 0.80 | ADRB3 (0.42) | F2F10PRSS1XIAPBIRC3 | |
| SCHEMBL7999967 | 0.80 | ADRB3 (0.42) | F2F10PRSS1XIAPBIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033654-B1 | Process for resolving a mixture of alkyl ester enantiomers using an enzyme | BRISTOL MYERS SQUIBB CO (US) | 2012-05-16 | — | — | EP | disclosed |
| EP-2086980-B1 | MACROCYCLIC PEPTIDES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2007015824-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2007-02-08 | — | — | WO | disclosed |