Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 3/20 | 0.33 |
| ▸ | PAM | P19021 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16451650 | 0.86 | KDM4E (0.36) | MAPTTHRBBLMKDM4EALOX15 | |
| SCHEMBL19879931 | 0.73 | ALDH1A1 (0.36) | CYP2D6HIF1AACEALDH1A1CYP3A4 | |
| SCHEMBL17377986 | 0.73 | KDM4E (0.55) | MAPTTHRBBLMKDM4EALOX15 | |
| SCHEMBL15033264 | 0.72 | — | — | |
| SCHEMBL19155459 | 0.71 | KDM4E (0.42) | MAPTTHRBBLMKDM4EALOX15 | |
| SCHEMBL13261389 | 0.71 | KDM4E (0.42) | MAPTTHRBBLMKDM4EALOX15 | |
| SCHEMBL15033316 | 0.70 | KDM4E (0.33) | MAPTTHRBBLMKDM4EALOX15 | |
| SCHEMBL10309809 | 0.70 | — | — | |
| SCHEMBL12843359 | 0.70 | — | — | |
| SCHEMBL17524675 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896715-B2 | Method for analyzing formyl glycine residue | JCR PHARMACEUTICALS CO., LTD. (JP) | 2018-02-20 | — | — | US | disclosed |
| US-20150044715-A1 | METHOD FOR ANALYZING FORMYL GLYCINE RESIDUE | JCR PHARMACEUTICALS CO., LTD. (JP) | 2015-02-12 | — | — | US | disclosed |