Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19879921 | 0.89 | — | — | |
| SCHEMBL16451649 | 0.73 | MAPT (0.40) | ALDH1A1ACECYP3A4CYP2C19CYP2D6 | |
| SCHEMBL25069812 | 0.68 | HDAC8 (0.35) | ALDH1A1CYP3A4 | |
| SCHEMBL10659188 | 0.66 | LMNA (0.40) | ALDH1A1USP2MITFKLF5ACE | |
| SCHEMBL10659184 | 0.66 | LMNA (0.40) | ALDH1A1USP2MITFKLF5ACE | |
| SCHEMBL30150927 | 0.62 | PTGS1 (0.43) | ALDH1A1 | |
| SCHEMBL22434813 | 0.62 | NAAA (0.49) | ALDH1A1USP2 | |
| SCHEMBL22404326 | 0.62 | NAAA (0.49) | ALDH1A1USP2 | |
| SCHEMBL16451650 | 0.61 | KDM4E (0.36) | ACE | |
| SCHEMBL18430289 | 0.60 | BCHE (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896715-B2 | Method for analyzing formyl glycine residue | JCR PHARMACEUTICALS CO., LTD. (JP) | 2018-02-20 | — | — | US | disclosed |