SCHEMBL16452136

SCHEMBL16452136

c1ccc(-c2cccc(-n3c4ccccc4c4cc5c6ccccc6n(-c6nc(-c7ccc8oc9ccccc9c8c7)nc(-c7ccc8oc9ccccc9c8c7)n6)c5cc43)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.36
PLA2G4A P47712 4/20 0.36
CHEK2 O96017 1/20 0.35
KDM4E B2RXH2 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 1/20 0.35
PLA2G10 O15496 1/20 0.34
HPSE Q9Y251 2/20 0.32
PGR P06401 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SIRT2 Q8IXJ6 1/20 0.31
SIRT1 Q96EB6 1/20 0.31
PRKDC P78527 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25008996 1.00 PLA2G2A (0.36) PLA2G2APLA2G4ACHEK2KDM4EL3MBTL1
SCHEMBL12691566 0.98 CHEK2 (0.35) PLA2G2APLA2G4ACHEK2KDM4EL3MBTL1
SCHEMBL20634227 0.96 PLA2G2A (0.37) PLA2G2APLA2G4ACHEK2KDM4EL3MBTL1
SCHEMBL23318012 0.96 PLA2G2A (0.37) PLA2G2APLA2G4ACHEK2KDM4EL3MBTL1
SCHEMBL16452140 0.95 PLA2G2A (0.36) PLA2G2APLA2G4ACHEK2KDM4EL3MBTL1
SCHEMBL17248181 0.95 KDM4E (0.35) PLA2G2APLA2G4ACHEK2KDM4EL3MBTL1
SCHEMBL19845504 0.95 PLA2G2A (0.37) PLA2G2APLA2G4ACHEK2KDM4EL3MBTL1
SCHEMBL16452355 0.95 CHEK2 (0.36) PLA2G2APLA2G4ACHEK2KDM4EL3MBTL1
SCHEMBL24914628 0.94 KDM4E (0.38) PLA2G2APLA2G4ACHEK2KDM4EL3MBTL1
SCHEMBL27441683 0.94 L3MBTL1 (0.35) PLA2G2APLA2G4ACHEK2KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9985219-B2 Organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2018-05-29 US disclosed
US-9985219-B2 Organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2018-05-29 US disclosed
US-20150041785-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-02-12 US disclosed
US-20150041785-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-02-12 US disclosed