SCHEMBL23318012

SCHEMBL23318012

c1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cccc(-c3nc(-c4ccc5oc6ccccc6c5c4)nc(-n4c5ccccc5c5ccccc54)n3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.37
PLA2G4A P47712 4/20 0.37
KDM4E B2RXH2 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ATM Q13315 1/20 0.36
CHEK2 O96017 1/20 0.36
PLA2G10 O15496 1/20 0.36
PTGER4 P35408 1/20 0.34
HPSE Q9Y251 2/20 0.33
TSPO P30536 1/20 0.33
PGR P06401 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20634227 1.00 PLA2G2A (0.37) PLA2G2APLA2G4AKDM4EL3MBTL1ATM
SCHEMBL19845504 0.99 PLA2G2A (0.37) PLA2G2APLA2G4AKDM4EL3MBTL1ATM
SCHEMBL19845501 0.98 PLA2G2A (0.37) PLA2G2APLA2G4AKDM4EL3MBTL1ATM
SCHEMBL23318013 0.97 PLA2G2A (0.39) PLA2G2APLA2G4AKDM4EL3MBTL1ATM
SCHEMBL16452136 0.96 PLA2G2A (0.36) PLA2G2APLA2G4AKDM4EL3MBTL1ATM
SCHEMBL25008996 0.96 PLA2G2A (0.36) PLA2G2APLA2G4AKDM4EL3MBTL1ATM
SCHEMBL18566013 0.96 CHEK2 (0.36) PLA2G2APLA2G4AKDM4EL3MBTL1ATM
SCHEMBL23317950 0.96 KDM4E (0.39) PLA2G2APLA2G4AKDM4EL3MBTL1ATM
SCHEMBL24352756 0.96 PLA2G2A (0.38) PLA2G2APLA2G4AKDM4EL3MBTL1ATM
SCHEMBL24303749 0.96 PLA2G2A (0.38) PLA2G2APLA2G4AKDM4EL3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210135118-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DOOSAN CORPORATION (KR) 2021-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210135118-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ELAVL1, EML4, ELAVL3 PLA2G2A 3436/4885PLA2G4A 3640/4885KDM4E 1670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.