Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862874 | 0.85 | RHEB (0.48) | RHEBHTR1AALOX15TSHRCYP1A2 | |
| SCHEMBL6872834 | 0.78 | RHEB (0.48) | RHEBDRD4DRD3ALDH1A1DRD2 | |
| SCHEMBL16450047 | 0.77 | TUBB4A (0.40) | LMNAKMT2AEGFRTUBB4ATUBB | |
| SCHEMBL11450500 | 0.75 | HTR1A (0.47) | RHEBHTR1AALOX15TSHRCYP1A2 | |
| SCHEMBL11451085 | 0.75 | RHEB (0.42) | RHEBTSHRCYP1A2CYP3A4LMNA | |
| SCHEMBL11460034 | 0.73 | ADRB2 (0.67) | HTR1AALOX15TSHRHSD17B10CYP1A2 | |
| SCHEMBL15297323 | 0.73 | HSD17B2 (0.43) | HSD17B10LMNAKDM4ETP53MAPK1 | |
| SCHEMBL25080566 | 0.73 | RHEB (0.50) | RHEBALOX15HSD17B10KDM4EGLA | |
| SCHEMBL11457356 | 0.72 | ADRB2 (0.48) | HTR1AALOX15TSHRCYP1A2CYP3A4 | |
| SCHEMBL23202761 | 0.72 | HSD17B10 (0.41) | ALOX15TSHRHSD17B10THRBHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9428493-B2 | Schweinfurthin analogues | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-08-30 | — | — | US | disclosed |
| US-20150045404-A1 | SCHWEINFURTHIN ANALOGUES | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045404-A1 | SCHWEINFURTHIN ANALOGUES | HRH4, HRH1, SUCNR1 | RHEB 1413/4885HTR1A 424/4885ALOX15 3276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.