Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740923 | 0.98 | MEN1 (0.48) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL30726502 | 0.98 | MEN1 (0.48) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL283740 | 0.98 | MEN1 (0.48) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL1495151 | 0.94 | ESR1 (0.47) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL30153131 | 0.94 | ESR1 (0.47) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL31678349 | 0.93 | ESR1 (0.46) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL19735694 | 0.92 | LMNA (0.43) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL19735693 | 0.92 | LMNA (0.43) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL21764711 | 0.89 | ESR1 (0.49) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL1645301 | 0.88 | SMN1; SMN2 (0.43) | MEN1KMT2ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227269-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| US-10573818-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-02-25 | — | — | US | disclosed |
| US-20170324037-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-11-09 | — | — | US | disclosed |
| US-20170324037-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-11-09 | — | — | US | disclosed |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| WO-2016087017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170324037-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME | AR, ARL1, ESR2 | MEN1 760/4885KMT2A 666/4885LMNA 1525/4885 |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, LEF1, EFNA1 | MEN1 472/4885KMT2A 2805/4885LMNA 2221/4885 |
| US-10573818-B2 | Materials for organic electroluminescent devices | PIEZO1, LEF1, EFNA1 | MEN1 472/4885KMT2A 2805/4885LMNA 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.