Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 4/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12361885 | 0.99 | RXRB (0.41) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL215438 | 0.94 | RXRB (0.42) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL212551 | 0.93 | RXRB (0.43) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL1645421 | 0.92 | TRPM8 (0.35) | RXRBRXRARXRGNPC1RAB9A | |
| Potassium SCHEMBL214696 | 0.92 | RXRB (0.42) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL214694 | 0.92 | RXRB (0.42) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL215440 | 0.92 | RXRB (0.42) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL1645082 | 0.92 | RAB9A (0.35) | NPC1RAB9A | |
| SCHEMBL12361965 | 0.90 | RXRA (0.45) | RXRBRXRARXRGNPC1RAB9A | |
| SCHEMBL12361951 | 0.90 | RXRA (0.45) | RXRBRXRARXRGNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314240-B2 | Sulfonamide compounds or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20110201616-A1 | SULFONAMIDE COMPOUNDS OR SALTS THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2305641-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201616-A1 | SULFONAMIDE COMPOUNDS OR SALTS THEREOF | PTGER1, PTGER2, GPER1 | RXRB 3083/4885RXRA 2466/4885RXRG 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.