Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454799 | 0.89 | NPSR1 (0.47) | ALDH1A1POLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL16454772 | 0.88 | MAPT (0.44) | ALDH1A1POLBBTKMAPTSMN1; SMN2 | |
| SCHEMBL16454907 | 0.88 | KDM4E (0.48) | ALDH1A1POLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL16454807 | 0.80 | HSD11B1 (0.38) | MAPTKMT2AMEN1LMNANPC1 | |
| SCHEMBL16454811 | 0.79 | HSD11B1 (0.46) | ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL16454796 | 0.79 | ALDH1A1 (0.43) | ALDH1A1POLBBTKMAPTSMN1; SMN2 | |
| SCHEMBL16454806 | 0.79 | KMT2A (0.49) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL16454800 | 0.78 | HSD11B1 (0.49) | BTKSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16454906 | 0.78 | GAA (0.45) | ALDH1A1POLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL16454857 | 0.77 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015020565-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[4,3-A]PYRIDINES EXHIBITING ANTAGONIST PROPERTIES TO ADENOSINE A2A RECEPTORS, AND USE THEREOF | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НЬЮВАК" (ООО "НЬЮВАК") (RU) | 2015-02-12 | — | — | WO | disclosed |