Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | GPX4 | P36969 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454805 | 0.90 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL16454908 | 0.88 | ALDH1A1 (0.47) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL16454899 | 0.82 | MEN1 (0.47) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL16454799 | 0.81 | NPSR1 (0.47) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL16454806 | 0.77 | KMT2A (0.49) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL16454907 | 0.77 | KDM4E (0.48) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL16454807 | 0.77 | HSD11B1 (0.38) | MAPTMEN1KMT2ARAB9ALMNA | |
| SCHEMBL16454800 | 0.75 | HSD11B1 (0.49) | MEN1KMT2ASMN1; SMN2BTK | |
| SCHEMBL16454906 | 0.74 | GAA (0.45) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL16454796 | 0.74 | ALDH1A1 (0.43) | MAPTMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015020565-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[4,3-A]PYRIDINES EXHIBITING ANTAGONIST PROPERTIES TO ADENOSINE A2A RECEPTORS, AND USE THEREOF | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НЬЮВАК" (ООО "НЬЮВАК") (RU) | 2015-02-12 | — | — | WO | disclosed |