Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031073 | 0.86 | MEN1 (0.55) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1031979 | 0.81 | PDE10A (0.55) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1035540 | 0.80 | MEN1 (0.54) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1033478 | 0.79 | PDE10A (0.58) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1033797 | 0.79 | XDH (0.46) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1031324 | 0.79 | MEN1 (0.46) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16542814 | 0.79 | CYP1A2 (0.55) | SMN1; SMN2HPGDMAPTALDH1A1NPC1 | |
| SCHEMBL30414157 | 0.79 | CYP1A2 (0.55) | SMN1; SMN2HPGDMAPTALDH1A1NPC1 | |
| SCHEMBL1034974 | 0.78 | MEN1 (0.49) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL10032275 | 0.77 | CYP1A1 (0.51) | MEN1KMT2ASMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8597798-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2013-12-03 | — | — | US | disclosed |
| EP-2344608-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2011-07-20 | — | — | EP | disclosed |
| US-20110095281-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
| WO-2010054731-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110095281-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SOD1, EPCAM, ICMT | PDE10A 3957/4885MEN1 1163/4885KMT2A 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.