Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 9/20 | 0.43 |
| ▸ | TGM2 | P21980 | 5/20 | 0.43 |
| ▸ | BCL3 | P20749 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18848622 | 0.89 | KMT2A (0.43) | KMT2AKDM1ATGM2BCL3CNR1 | |
| SCHEMBL18848623 | 0.79 | KDM1A (0.44) | KDM1ATGM2 | |
| SCHEMBL18059540 | 0.79 | KDM1A (0.44) | KDM1ATGM2 | |
| SCHEMBL16455182 | 0.76 | KDM1A (0.53) | KMT2AKDM1ATGM2MEN1 | |
| SCHEMBL20924673 | 0.73 | KDM1A (0.51) | KDM1A | |
| SCHEMBL16455163 | 0.72 | KDM1A (0.53) | KDM1ATGM2 | |
| SCHEMBL16447253 | 0.72 | KDM1A (0.53) | KDM1A | |
| SCHEMBL16447254 | 0.72 | KDM1A (0.53) | KDM1A | |
| SCHEMBL16447279 | 0.71 | KDM1A (0.51) | KDM1A | |
| SCHEMBL16447281 | 0.71 | KDM1A (0.51) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021128-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES INC. (US) | 2015-02-12 | — | — | WO | disclosed |