Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.42 |
| ▸ | PPARA | Q07869 | 14/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847400 | 0.87 | PPARA (0.41) | PPARGPPARAPPARD | |
| SCHEMBL16456485 | 0.80 | PGR (0.41) | PPARGPPARAPPARDALDH1A1LMNA | |
| SCHEMBL543847 | 0.80 | PPARG (0.64) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL6075851 | 0.79 | PPARA (0.46) | PPARGPPARAPPARDPTGER4ALDH1A1 | |
| SCHEMBL543498 | 0.78 | PPARG (0.55) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL16456489 | 0.78 | DRD3 (0.42) | PPARGPPARAPPARDALDH1A1LMNA | |
| SCHEMBL16456500 | 0.77 | PPARA (0.44) | PPARGPPARAPPARDALDH1A1LMNA | |
| SCHEMBL6396442 | 0.77 | PPARA (0.48) | PPARGPPARAPPARDALDH1A1LMNA | |
| SCHEMBL6076525 | 0.76 | PPARG (0.48) | PPARGPPARAPPARDPTGER4ALDH1A1 | |
| SCHEMBL16456491 | 0.75 | PPARG (0.44) | PPARGPPARAPPARDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250323-B1 | Compounds having hypolipidemic and hypocholesterolemic activities, process for their preparation and pharmaceutical compositions containing them | CADILA HEALTHCARE LTD (IN) | 2014-01-01 | — | — | EP | claimed |