SCHEMBL5847400

SCHEMBL5847400

CCOC(CC)(Cc1ccc(OCCn2c(C(C)C)cc(-c3ccccc3)c2-c2ccc(F)cc2)cc1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 10/20 0.41
PPARG P37231 7/20 0.41
PPARD Q03181 6/20 0.41
HMGCR P04035 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16456487 0.87 PPARG (0.42) PPARAPPARGPPARD
SCHEMBL543247 0.82 PPARG (0.58) PPARAPPARGPPARD
SCHEMBL543539 0.80 PPARA (0.50) PPARAPPARGPPARD
SCHEMBL6075851 0.79 PPARA (0.46) PPARAPPARGPPARD
SCHEMBL542804 0.78 PGR (0.50) PPARAPPARGPPARD
SCHEMBL16456485 0.76 PGR (0.41) PPARAPPARGPPARD
SCHEMBL16456489 0.75 DRD3 (0.42) PPARAPPARGPPARD
SCHEMBL6076525 0.74 PPARG (0.48) PPARAPPARGPPARD
SCHEMBL16456500 0.74 PPARA (0.44) PPARAPPARGPPARD
SCHEMBL6396442 0.73 PPARA (0.48) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1250323-B1 Compounds having hypolipidemic and hypocholesterolemic activities, process for their preparation and pharmaceutical compositions containing them CADILA HEALTHCARE LTD (IN) 2014-01-01 EP claimed
US-6987123-B2 Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine CADILA HEALTHCARE LIMITED (IN) 2006-01-17 US claimed