Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295180 | 0.82 | SCN9A (0.47) | FAAHHDAC1NAMPTCARM1PRMT6 | |
| SCHEMBL31473430 | 0.82 | SCN9A (0.47) | FAAHHDAC1NAMPTCARM1PRMT6 | |
| SCHEMBL1444314 | 0.81 | HPGD (0.59) | FAAHNAMPTL3MBTL1 | |
| SCHEMBL4616649 | 0.81 | MAPK14 (0.53) | HDAC1NAMPTL3MBTL1 | |
| SCHEMBL8214975 | 0.81 | HDAC1 (0.50) | HDAC1NAMPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27698235 | 0.80 | HPGD (0.58) | FAAHNAMPTL3MBTL1 | |
| SCHEMBL3180689 | 0.79 | L3MBTL1 (0.61) | HDAC1NAMPTL3MBTL1 | |
| SCHEMBL184462 | 0.79 | GRM2 (0.48) | FAAHHDAC1NAMPT | |
| SCHEMBL16192942 | 0.78 | FAAH (0.57) | FAAHHDAC1NAMPTL3MBTL1 | |
| SCHEMBL3838871 | 0.78 | CA12 (0.63) | HDAC1NAMPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-B1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2014-04-16 | — | — | EP | disclosed |