Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248401 | 0.95 | KMT2A (0.66) | KMT2ALMNASMN1; SMN2BRD4POLB | |
| SCHEMBL7952997 | 0.94 | KMT2A (0.64) | KMT2ALMNASMN1; SMN2BRD4POLB | |
| SCHEMBL11482525 | 0.94 | KMT2A (0.64) | KMT2ALMNASMN1; SMN2BRD4POLB | |
| SCHEMBL14625066 | 0.94 | KMT2A (0.64) | KMT2ALMNASMN1; SMN2BRD4POLB | |
| SCHEMBL7959649 | 0.92 | RAB9A (0.67) | KMT2ALMNASMN1; SMN2BRD4POLB | |
| SCHEMBL9570553 | 0.90 | LMNA (0.67) | KMT2ALMNASMN1; SMN2BRD4POLB | |
| SCHEMBL9570675 | 0.90 | LMNA (0.67) | KMT2ALMNASMN1; SMN2BRD4POLB | |
| SCHEMBL11546122 | 0.90 | LMNA (0.75) | KMT2ALMNASMN1; SMN2BRD4POLB | |
| SCHEMBL6838359 | 0.87 | KMT2A (0.68) | KMT2ALMNASMN1; SMN2POLBTSHR | |
| SCHEMBL1545262 | 0.87 | LMNA (0.63) | KMT2ALMNASMN1; SMN2BRD4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5075325-A | Cardiovascular disorders | SYNTHELABO (FR) | 1991-12-24 | — | — | US | disclosed |
| US-5001159-A | Hypotensive, antiulcer, antiischemic agents; migraines, asthma epilepsy, anticoagulants; cardiovasculat disorders | SYNTHELABO (FR) | 1991-03-19 | — | — | US | disclosed |
| EP-0292911-A2 | Process for the preparation of pure nitro-aminobenzene-compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |