SCHEMBL1645844

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL943023	0.85	MAPT (0.55)	MAPTGFERADRA2CKDM4ELMNA
	SCHEMBL942660	0.81	GAA (0.55)	MAPTGFERKDM4ELMNATSHR
	SCHEMBL942722	0.81	MAPT (0.51)	MAPTGFERADRA2CKDM4ELMNA
	SCHEMBL1127038	0.79	PHGDH (0.47)	MAPTGFERKDM4ELMNATSHR
	SCHEMBL1019837	0.79	MAPT (0.46)	MAPTGFERKDM4ELMNATSHR
	SCHEMBL943720	0.78	MAPT (0.56)	MAPTGFERKDM4ELMNAIRAK4
	SCHEMBL943333	0.77	MAPT (0.56)	MAPTGFERKDM4EALDH1A1POLB
	SCHEMBL6942579	0.77	ADRA2C (0.80)	MAPTGFERADRA2CKDM4ELMNA
	SCHEMBL942659	0.76	MAPT (0.40)	MAPTGFERKDM4ELMNATSHR
	Hydrochloric Acid SCHEMBL7077636	0.75	ADRA2C (0.77)	MAPTGFERADRA2CKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.