SCHEMBL1019837

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL942660	0.86	GAA (0.55)	MAPTGFERPHGDHLMNASMN1; SMN2
	SCHEMBL1127038	0.84	PHGDH (0.47)	MAPTGFERPHGDHLMNASMN1; SMN2
	SCHEMBL943023	0.81	MAPT (0.55)	MAPTGFERLMNASMN1; SMN2ALOX12
	SCHEMBL1645844	0.79	MAPT (0.56)	MAPTGFERPHGDHLMNADHFR
	SCHEMBL15358734	0.79	MAPT (0.63)	MAPTGFERLMNASMN1; SMN2ALOX12
	SCHEMBL942935	0.79	HPGD (0.46)	MAPTPHGDHLMNASMN1; SMN2L3MBTL1
	SCHEMBL1021026	0.79	MAPT (0.42)	MAPTGFERPHGDHLMNASMN1; SMN2
	SCHEMBL1126980	0.79	HPGD (0.46)	MAPTPHGDHLMNASMN1; SMN2L3MBTL1
	SCHEMBL942722	0.78	MAPT (0.51)	MAPTGFERLMNASMN1; SMN2ALOX12
	SCHEMBL943333	0.77	MAPT (0.56)	MAPTGFERPHGDHSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.