SCHEMBL1127038

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL942660	0.86	GAA (0.55)	PHGDHMAPTGFERKDM4ELMNA
	SCHEMBL1019837	0.84	MAPT (0.46)	PHGDHMAPTGFERKDM4ELMNA
	SCHEMBL943023	0.81	MAPT (0.55)	MAPTGFERKDM4ELMNAMEN1
	SCHEMBL1645844	0.79	MAPT (0.56)	PHGDHMAPTGFERKDM4ELMNA
	SCHEMBL17265646	0.79	MAPT (0.52)	MAPTGFERKDM4ELMNAMEN1
	SCHEMBL1021026	0.79	MAPT (0.42)	PHGDHMAPTGFERKDM4ELMNA
	SCHEMBL942722	0.78	MAPT (0.51)	MAPTGFERKDM4ELMNAMEN1
	SCHEMBL942120	0.76	MAPT (0.63)	MAPTGFERLMNAKMT2AMAPK1
	SCHEMBL14239598	0.75	GAA (0.67)	MAPTGFERKDM4ELMNAMEN1
	SCHEMBL942805	0.73	SIRT6 (0.56)	MAPTLMNAMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.