SCHEMBL1645852

SCHEMBL1645852

SCN1CNc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 1/20 0.38
EPHX2 P34913 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 1/20 0.35
ALOX12 P18054 1/20 0.33
HSD17B3 P37058 1/20 0.33
BRD4 O60885 1/20 0.33
ACHE P22303 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CDK4 P11802 1/20 0.31
ALOX15 P16050 1/20 0.31
CCND1 P24385 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6450576 0.83 BRPF1 (0.44) BRPF1EPHX2MEN1KMT2AGAA
SCHEMBL9868798 0.80 GRIA2 (0.44) BRPF1EPHX2MEN1KMT2AGAA
SCHEMBL7544166 0.77 GAA (0.42) BRPF1EPHX2MEN1KMT2AGAA
SCHEMBL9304274 0.77 EPHX2 (0.57) EPHX2KMT2AALOX12BRD4ACHE
SCHEMBL10680826 0.77 BRPF1 (0.40) BRPF1EPHX2MEN1KMT2AGAA
SCHEMBL7854100 0.77 MEN1 (0.44) BRPF1EPHX2MEN1KMT2AGAA
SCHEMBL8793695 0.76 KMT2A (0.42) BRPF1EPHX2MEN1KMT2AGAA
SCHEMBL6690571 0.76 BRPF1 (0.35) BRPF1EPHX2MEN1KMT2AGAA
SCHEMBL30022234 0.76 EPHX2 (0.55) EPHX2KMT2AALOX12BRD4ACHE
SCHEMBL8039565 0.76 BRPF1 (0.39) BRPF1EPHX2MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562877-A1 RUBBER MIXTURES ARLANXEO Deutschland GmbH (DE) 2019-11-06 EP disclosed
EP-3505366-A1 NEW RUBBER MIXTURES ARLANXEO Deutschland GmbH (DE) 2019-07-03 EP disclosed
EP-3505523-A1 NEW RUBBER MIXTURES ARLANXEO Deutschland GmbH (DE) 2019-07-03 EP disclosed
EP-2812392-B1 BEARING SURFACE MIXTURE CONTAINING MICRO-GEL FOR WINTER TYRES ARLANXEO DEUTSCHLAND GMBH (DE) 2018-08-22 EP disclosed
WO-2018121976-A1 RUBBER MIXTURES ARLANXEO DEUTSCHLAND GMBH (DE) 2018-07-05 WO disclosed
EP-3060412-B1 RUBBER COMPOUND ARLANXEO DEUTSCHLAND GMBH (DE) 2018-06-27 EP disclosed
US-9938398-B2 Rubber composition ARLANXEO DEUTSCHLAND GMBH (DE) 2018-04-10 US disclosed
US-20160237259-A1 RUBBER COMPOSITION ARLANXEO DEUTSCHLAND GMBH (DE) 2016-08-18 US disclosed
EP-2865540-A1 Rubber compound LANXESS Deutschland GmbH (DE) 2015-04-29 EP disclosed
US-20150031790-A1 MICROGEL-CONTAINING TREAD MIXTURE FOR WINTER TYRES ARLANXEO DEUTSCHLAND GMBH (DE) 2015-01-29 US disclosed
EP-2626384-A1 Bearing surface mixture containing micro-gel for winter tyres Lanxess Deutschland GmbH (DE) 2013-08-14 EP disclosed
EP-2491077-A1 NOVEL RUBBER MIXTURES Lanxess Deutschland GmbH (DE) 2012-08-29 EP disclosed
WO-2011048034-A1 NOVEL RUBBER MIXTURES LANXESS DEUTSCHLAND GMBH (DE) 2011-04-28 WO disclosed
EP-2311907-A1 New rubber mixtures LANXESS Deutschland GmbH (DE) 2011-04-20 EP disclosed
EP-2196496-A2 Additive compound Rhein Chemie Rheinau GmbH (DE) 2010-06-16 EP disclosed