Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175819 | 0.86 | PTGS1 (0.42) | BRPF1EPHX2HSD17B3HDAC2HDAC8 | |
| SCHEMBL6693798 | 0.81 | EPHX2 (0.38) | BRPF1EPHX2HSD17B3HDAC2HDAC8 | |
| SCHEMBL14309648 | 0.80 | SLC6A2 (0.52) | SLC6A2 | |
| SCHEMBL6450576 | 0.79 | BRPF1 (0.44) | BRPF1EPHX2HSD17B3GAAMEN1 | |
| SCHEMBL7544166 | 0.76 | GAA (0.42) | BRPF1EPHX2GAAMEN1KMT2A | |
| SCHEMBL1645852 | 0.76 | BRPF1 (0.38) | BRPF1EPHX2HSD17B3GAAMEN1 | |
| SCHEMBL9868798 | 0.76 | GRIA2 (0.44) | BRPF1EPHX2HSD17B3GAAMEN1 | |
| SCHEMBL8793695 | 0.75 | KMT2A (0.42) | BRPF1EPHX2HSD17B3GAAMEN1 | |
| SCHEMBL31285850 | 0.75 | KMT2A (0.42) | BRPF1EPHX2HSD17B3GAAMEN1 | |
| SCHEMBL8039565 | 0.75 | BRPF1 (0.39) | BRPF1EPHX2HSD17B3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005407-A2 | TETRA-AZAPENTAMETHINE AND USE THEREOF FOR DYEING KERATINOUS FIBERS | L'OREAL (FR) | 2004-01-15 | — | — | WO | claimed |
| WO-2004005407-A2 | TETRA-AZAPENTAMETHINE AND USE THEREOF FOR DYEING KERATINOUS FIBERS | L'OREAL (FR) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378544-A2 | Tetraaza-pentamethine derivatives and their application for dyeing keratinous fibres | L'OREAL (FR) | 2004-01-07 | — | — | EP | disclosed |