Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316153 | 0.84 | GAA (0.39) | GAAALDH1A1GRIA1GRIA2GRIA3 | |
| SCHEMBL8039565 | 0.84 | BRPF1 (0.39) | GAABRPF1EPHX2KMT2AMEN1 | |
| SCHEMBL8756210 | 0.82 | KMT2A (0.43) | GAAALDH1A1GRIA1GRIA2GRIA3 | |
| SCHEMBL29169523 | 0.80 | GAA (0.31) | GAABRPF1EPHX2 | |
| SCHEMBL6450576 | 0.80 | BRPF1 (0.44) | GAAALDH1A1ADRA1AKDM4EBRPF1 | |
| SCHEMBL1645852 | 0.77 | BRPF1 (0.38) | GAAALDH1A1BRPF1EPHX2KMT2A | |
| SCHEMBL9868798 | 0.77 | GRIA2 (0.44) | GAAALDH1A1GRIA2BRPF1EPHX2 | |
| SCHEMBL6690571 | 0.76 | BRPF1 (0.35) | GAABRPF1EPHX2KMT2AMEN1 | |
| SCHEMBL8469492 | 0.76 | GRIA2 (0.43) | GAAALDH1A1GRIA1GRIA2GRIA3 | |
| SCHEMBL8523950 | 0.76 | GRIA2 (0.37) | GAAALDH1A1GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202985-A2 | CHEMOKINE RECEPTOR ANTAGONISTS | Millennium Pharmaceuticals, Inc. (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001009119-A2 | CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-02-08 | — | — | WO | disclosed |
| EP-1049700-A1 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREFOR | Millennium Pharmaceuticals, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037651-A1 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREFOR | MILLENIUM PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
| EP-0431425-A2 | Chromogen enamine compounds, their preparation and use as colour formers | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |
| EP-0262343-A2 | N-alkylated quaternary nitrogen-containing heterocycles, process for their preparation and their use in pharmaceutical compositions | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1988-04-06 | — | — | EP | disclosed |