Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.48 |
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16458597 | 1.00 | CTSS (0.48) | CTSSCTSKTACR1CTSLCTSB | |
| SCHEMBL16478949 | 0.91 | CTSS (0.47) | CTSSCTSKTACR1CTSLCTSB | |
| SCHEMBL16459992 | 0.87 | CTSS (0.64) | CTSSCTSKTACR1CTSLCTSB | |
| SCHEMBL28247795 | 0.87 | CTSS (0.47) | CTSSCTSKTACR1CTSLCTSB | |
| SCHEMBL16459991 | 0.87 | CTSS (0.64) | CTSSCTSKTACR1CTSLCTSB | |
| SCHEMBL16459632 | 0.85 | CTSS (0.66) | CTSSCTSKTACR1CTSLTP53 | |
| SCHEMBL16459631 | 0.85 | CTSS (0.66) | CTSSCTSKTACR1CTSLTP53 | |
| SCHEMBL269930 | 0.85 | ACE (0.58) | CTSSCTSKCTSLCTSBJAK2 | |
| SCHEMBL269929 | 0.85 | ACE (0.58) | CTSSCTSKCTSLCTSBJAK2 | |
| SCHEMBL873556 | 0.85 | ACE (0.58) | CTSSCTSKCTSLCTSBJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140012005-A1 | PROCESS FOR PREPARING CHIRAL AMINO ACIDS | DIVERCHIM (FR) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012005-A1 | PROCESS FOR PREPARING CHIRAL AMINO ACIDS | BCAT1, DNPEP, BCAT2 | CTSS 724/4885CTSK 2248/4885TACR1 1492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.