Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1300340 | 1.00 | LMNA (0.41) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL4409246 | 0.89 | LMNA (0.39) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL4409249 | 0.89 | LMNA (0.39) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL16461663 | 0.88 | MAPT (0.40) | MAPTHPGDSMN1; SMN2PAX8ALDH1A1 | |
| SCHEMBL16461664 | 0.88 | MAPT (0.40) | MAPTHPGDSMN1; SMN2PAX8ALDH1A1 | |
| SCHEMBL12108808 | 0.88 | CA1 (0.38) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL16462013 | 0.85 | KMT2A (0.41) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL16462011 | 0.85 | KMT2A (0.41) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL2181651 | 0.84 | CYP11B1 (0.41) | MEN1KMT2AHPGDL3MBTL1PAX8 | |
| SCHEMBL2181660 | 0.84 | CYP11B1 (0.41) | MEN1KMT2AHPGDL3MBTL1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906529-B9 | A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR | ZENTIVA KS (CZ) | 2017-03-15 | — | — | EP | disclosed |
| EP-2906529-B1 | A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR | ZENTIVA KS (CZ) | 2016-11-23 | — | — | EP | disclosed |
| EP-2906529-A1 | A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR | Zentiva K.S. (CZ) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014056464-A1 | A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR | ZENTIVA, K.S. (CZ) | 2014-04-17 | — | — | WO | disclosed |
| US-20130345462-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | JAPAN TOBACCO INC. (JP) | 2013-12-26 | — | — | US | disclosed |
| US-8420821-B2 | Process for production of 4-oxoquinoline compound | JAPAN TOBACCO INC. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420821-B2 | Process for production of 4-oxoquinoline compound | JAPAN TOBACCO INC. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20110269741-A1 | NOVEL COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES, INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269741-A1 | NOVEL COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES, INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110166123-A1 | NOVEL COMPOSITIONS AND METHODS OF USE | AARDEA BIOSCIENCES, INC. (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110166123-A1 | NOVEL COMPOSITIONS AND METHODS OF USE | AARDEA BIOSCIENCES, INC. (US) | 2011-07-07 | — | — | US | disclosed |
| EP-2231665-A2 | NOVEL COMPOSITIONS AND METHODS OF USE | Ardea Biosciences, Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| WO-2009089263-A2 | NOVEL COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES INC. (US) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130345462-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | CYP4X1, CYP3A4, CYP3A7 | LMNA 2635/4885MAPT 4765/4885MEN1 3040/4885 |
| US-20110166123-A1 | NOVEL COMPOSITIONS AND METHODS OF USE | TYMP, SAMHD1, PNP | LMNA 1312/4885MAPT 3259/4885MEN1 4555/4885 |
| US-20090318702-A1 | PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND | CYP4X1, CYP3A4, CYP3A7 | LMNA 2635/4885MAPT 4765/4885MEN1 3040/4885 |
| US-20110269741-A1 | NOVEL COMPOSITIONS AND METHODS OF USE | TYMP, SAMHD1, PNP | LMNA 1312/4885MAPT 3259/4885MEN1 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.