SCHEMBL1646290

SCHEMBL1646290

Clc1ccc(CCSSCCc2ccc(Cl)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.55
TAAR1 Q96RJ0 2/20 0.54
MAOB P27338 1/20 0.46
AOC3 Q16853 1/20 0.45
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
HTR3A P46098 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
MIF P14174 1/20 0.43
LMNA P02545 2/20 0.43
ALPG P10696 1/20 0.43
HTT P42858 1/20 0.43
CYP2A6 P11509 1/20 0.42
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42
GPR84 Q9NQS5 2/20 0.41
SLC6A4 P31645 1/20 0.41
AGXT P21549 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6011707 0.84 IDO1 (0.55) IDO1TAAR1MAOBAOC3HTR3E
SCHEMBL1145548 0.80 IDO1 (0.52) IDO1TAAR1MAOBAOC3HTR3E
SCHEMBL1145549 0.80 IDO1 (0.52) IDO1TAAR1MAOBAOC3HTR3E
SCHEMBL2135113 0.80 TAAR1 (0.68) IDO1TAAR1MAOBAOC3HTR3E
SCHEMBL13799439 0.77 IDO1 (0.48) IDO1TAAR1MAOBAOC3LMNA
SCHEMBL5976654 0.77 IDO1 (0.48) IDO1TAAR1MAOBAOC3HTR3E
SCHEMBL8196751 0.76 SIGMAR1 (0.58) TAAR1MAOBLMNAALOX15
SCHEMBL27294675 0.75 IDO1 (0.47) IDO1TAAR1MAOBAOC3HTR3E
SCHEMBL10365734 0.75 IGF1R (0.64) IDO1TAAR1MAOBAOC3HTR3E
SCHEMBL18050371 0.75 TAAR1 (0.62) IDO1TAAR1MAOBAOC3HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed
EP-0022634-A1 Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them TEIJIN LIMITED (JP) 1981-01-21 EP disclosed