Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11188168 | 0.97 | SIGMAR1 (0.56) | SIGMAR1MAOAMAOBTAAR1TSHR | |
| SCHEMBL14219298 | 0.93 | CYP1A2 (0.64) | SIGMAR1MAOAMAOBTAAR1MEN1 | |
| SCHEMBL10812127 | 0.90 | HTR2A (0.60) | SIGMAR1MAOAMAOBTAAR1MEN1 | |
| SCHEMBL2135113 | 0.88 | TAAR1 (0.68) | MAOBTAAR1LMNAALOX15 | |
| SCHEMBL12040532 | 0.87 | MAOB (0.58) | SIGMAR1MAOAMAOBALDH1A1PLAAT3 | |
| SCHEMBL8723191 | 0.87 | MAOB (0.58) | SIGMAR1MAOAMAOBALDH1A1PLAAT3 | |
| SCHEMBL13658171 | 0.87 | NR1D1 (0.51) | SIGMAR1MAOAMAOBTAAR1MEN1 | |
| SCHEMBL11855324 | 0.87 | MEN1 (0.47) | SIGMAR1MAOAMAOBTAAR1MEN1 | |
| SCHEMBL55138 | 0.85 | MAOB (0.72) | SIGMAR1MAOAMAOBTAAR1ALDH1A1 | |
| SCHEMBL12506236 | 0.85 | MAOB (0.72) | SIGMAR1MAOAMAOBTAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101735116-B | Sulfonated aromatic diamine and sulfonated polyimide resin and preparation methods thereof | CHINESE ACAD INST CHEMISTRY | 2013-08-07 | — | — | CN | claimed |
| CN-103130592-A | Synthetic method for diaryl methane derivatives | UNIV CHONGQING | 2013-06-05 | — | — | CN | claimed |
| CN-101735116-A | Sulfonated aromatic diamine and sulfonated polyimide resin and preparation methods thereof | CHINESE ACAD INST CHEMISTRY | 2010-06-16 | — | — | CN | claimed |
| CN-114345370-B | Method for reduction cross coupling of photocatalytic aromatic olefin and halogenated hydrocarbon | 陕西师范大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-111704548-B | Method for preparing nitroolefin from aryl ethane and nitrate | 郑州师范学院 | 2023-04-25 | — | — | CN | disclosed |
| CN-114591138-A | Preparation method of bibenzyl compound | 青岛伯川特聚科技有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114345370-A | Method for reducing and cross-coupling aromatic olefin and halogenated hydrocarbon through photocatalysis | 陕西师范大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-113660983-A | Carbamate derivatives and uses thereof | 诺瑟拉有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2020198464-A1 | HIGHLY SELECTIVE ELECTROCHEMICAL HYDROGENATION OF ALKYNES | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2020-10-01 | — | — | WO | disclosed |
| CN-111704548-A | Method for preparing nitroolefin from aryl ethane and nitrate | 郑州师范学院 | 2020-09-25 | — | — | CN | disclosed |
| WO-2020012403-A1 | AN IMPROVED PROCESS FOR DIASTER-EOSELECTIVE SYNTHESIS OF VICINAL DIAMINES | Piramal Enterprises Limited (IN) | 2020-01-16 | — | — | WO | disclosed |
| EP-0723525-A4 | PROCESS FOR DECREASING CHLORINE CONTENT IN CHLORINATED HYDROCARBONS | UNIV PRINCETON (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0723525-A1 | PROCESS FOR DECREASING CHLORINE CONTENT IN CHLORINATED HYDROCARBONS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995010484-A1 | PROCESS FOR DECREASING CHLORINE CONTENT IN CHLORINATED HYDROCARBONS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1995-04-20 | — | — | WO | disclosed |
| US-5159117-A | Reacting ketone or aldehyde with nitrites in presence of acid catalyst | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |
| EP-0472118-A1 | Process for production of alpha,alpha-dialkoxycetones | BASF Aktiengesellschaft (DE) | 1992-02-26 | — | — | EP | disclosed |
| US-4431660-A | UROGENITAL DISORDERS; ENZYME INHIBITORS; KIDNEY AND BLADDER STONES | MERCK & CO., INC. (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0021228-B1 | 4-SUBSTITUTED-3-HYDROXY-3-PYRROLINE-2,5-DIONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | MERCK & CO. INC. (US) | 1982-09-01 | — | — | EP | disclosed |
| US-4256758-A | 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase | MERCK & CO., INC. (US) | 1981-03-17 | — | — | US | disclosed |
| EP-0021228-A1 | 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione compounds, process for their preparation and pharmaceutical compositions containing the same | MERCK & CO. INC. (US) | 1981-01-07 | — | — | EP | disclosed |