Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | DHPS | P49366 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.32 |
| ▸ | CDK1 | P06493 | 6/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.32 |
| ▸ | CDK2 | P24941 | 5/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16465235 | 0.91 | APP (0.37) | APPTLR8TLR7 | |
| SCHEMBL16462888 | 0.90 | CDK1 (0.35) | TLR8TLR7CDK1CCNB1CCNA2 | |
| SCHEMBL16462886 | 0.86 | ADORA3 (0.33) | ADORA3ADORA1 | |
| SCHEMBL16464333 | 0.85 | CDK1 (0.33) | TLR8TLR7CDK1CCNB1CCNA2 | |
| SCHEMBL16485072 | 0.85 | CDK1 (0.45) | TLR8TLR7CDK1CCNB1CCNA2 | |
| SCHEMBL16464464 | 0.84 | TLR8 (0.36) | TLR8TLR7CDK1CCNB1CCNA2 | |
| SCHEMBL16482380 | 0.83 | TLR8 (0.35) | TLR8TLR7CDK1CCNB1CCNA2 | |
| SCHEMBL16464561 | 0.83 | TLR7 (0.47) | TLR8TLR7CDK1CCNB1CCNA2 | |
| SCHEMBL16852165 | 0.82 | CDK1 (0.35) | DHPSCDK1CCNB1CCNA2CDK2 | |
| SCHEMBL16465508 | 0.81 | SMN1; SMN2 (0.37) | TLR8TLR7CDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9364408-B2 | Hair dye agent comprising aminopyrimidine derivatives | HENKEL AG & CO. KGAA (DE) | 2016-06-14 | — | — | US | claimed |
| EP-2906191-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | Henkel AG&Co. KGAA (DE) | 2015-08-19 | — | — | EP | claimed |
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2015-07-30 | — | — | US | claimed |
| WO-2014056760-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2014-04-17 | — | — | WO | claimed |
| US-9364408-B2 | Hair dye agent comprising aminopyrimidine derivatives | HENKEL AG & CO. KGAA (DE) | 2016-06-14 | — | — | US | disclosed |
| US-9364408-B2 | Hair dye agent comprising aminopyrimidine derivatives | HENKEL AG & CO. KGAA (DE) | 2016-06-14 | — | — | US | disclosed |
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2015-07-30 | — | — | US | disclosed |
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2015-07-30 | — | — | US | disclosed |
| WO-2014056760-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2014-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | KRT18, DPYD, DHFR | APP 2946/4885DHPS 98/4885TLR8 3565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.