Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463705 | 0.87 | ADORA3 (0.30) | ADORA3ADORA1 | |
| SCHEMBL16463516 | 0.86 | APP (0.33) | ADORA3ADORA1 | |
| SCHEMBL16465508 | 0.84 | SMN1; SMN2 (0.37) | NUDT1CHUK | |
| SCHEMBL16462888 | 0.83 | CDK1 (0.35) | ADORA3ADORA1NUDT1CHUK | |
| SCHEMBL16481914 | 0.82 | CHUK (0.30) | CHUK | |
| SCHEMBL16465235 | 0.81 | APP (0.37) | — | |
| SCHEMBL16482165 | 0.81 | TLR8 (0.33) | — | |
| SCHEMBL16485072 | 0.81 | CDK1 (0.45) | — | |
| SCHEMBL16852215 | 0.80 | NUDT1 (0.34) | NUDT1 | |
| SCHEMBL16482380 | 0.79 | TLR8 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9364408-B2 | Hair dye agent comprising aminopyrimidine derivatives | HENKEL AG & CO. KGAA (DE) | 2016-06-14 | — | — | US | claimed |
| EP-2906191-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | Henkel AG&Co. KGAA (DE) | 2015-08-19 | — | — | EP | claimed |
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2015-07-30 | — | — | US | claimed |
| WO-2014056760-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2014-04-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | KRT18, DPYD, DHFR | ADORA3 3000/4885ADORA1 2188/4885NUDT1 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.