Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16462440 | 0.82 | P2RX7 (0.51) | P2RX7CNR2 | |
| SCHEMBL16462927 | 0.81 | P2RX7 (0.42) | P2RX7CNR2 | |
| SCHEMBL19464702 | 0.74 | FOS (0.32) | P2RX7 | |
| SCHEMBL2616425 | 0.72 | P2RX7 (0.32) | P2RX7 | |
| SCHEMBL22778748 | 0.69 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL23259090 | 0.68 | GRM2 (0.38) | — | |
| SCHEMBL22001877 | 0.68 | CYP19A1 (0.34) | — | |
| SCHEMBL8774959 | 0.67 | ALDH1A1 (0.33) | P2RX7 | |
| SCHEMBL8774938 | 0.67 | ALDH1A1 (0.33) | P2RX7 | |
| SCHEMBL8774949 | 0.67 | ALDH1A1 (0.33) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906546-A1 | BENZAMIDES | H. Lundbeck A/S (DK) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014057078-A1 | BENZAMIDES | H. LUNDBECK A/S (DK) | 2014-04-17 | — | — | WO | disclosed |