SCHEMBL16466907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4459057	0.88	PRKCA (0.44)	KMT2AMEN1MAPT
	SCHEMBL7286996	0.82	POLB (0.45)	KMT2AMEN1POLBMAPTLMNA
	SCHEMBL7559265	0.78	KMT2A (0.50)	KMT2AMEN1NPSR1SMN1; SMN2TSHR
	SCHEMBL10919474	0.76	KDM4E (0.38)	KMT2ASMN1; SMN2MAPTLMNASLC18A3
	SCHEMBL10917834	0.74	POLB (0.43)	KMT2AMEN1POLBALDH1A1
	SCHEMBL27720908	0.73	SSTR4 (0.40)	KMT2AMEN1NPSR1SMN1; SMN2TSHR
	SCHEMBL27864062	0.72	POLB (0.47)	KMT2AMEN1NPSR1SMN1; SMN2TSHR
	SCHEMBL10918509	0.72	PRKCA (0.45)	POLB
	SCHEMBL10915144	0.72	PRKCA (0.45)	POLB
	SCHEMBL27535325	0.71	ALDH1A1 (0.46)	KMT2AMEN1NPSR1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.