Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10917834 | 0.92 | POLB (0.43) | POLBKMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10918616 | 0.90 | PRKCA (0.43) | POLB | |
| SCHEMBL10918509 | 0.89 | PRKCA (0.45) | POLB | |
| SCHEMBL10915144 | 0.89 | PRKCA (0.45) | POLB | |
| SCHEMBL10921650 | 0.88 | POLB (0.44) | POLBKMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28038717 | 0.85 | ALDH1A1 (0.41) | POLBALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL10914280 | 0.85 | KMT2A (0.39) | POLBKMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL10920011 | 0.84 | KMT2A (0.36) | POLBKMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL10917903 | 0.83 | TSHR (0.42) | POLBKMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL10919884 | 0.82 | MTNR1B (0.37) | POLBKMT2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007036-A4 | METHODS OF USING BUTYRIC ACID OR BUTYRIC ACID DERIVATIVES TO PROTECT AGAINST HAIR LOSS | UNIV BAR ILAN (IL) | 2001-02-28 | — | — | EP | claimed |
| EP-1007036-A1 | METHODS OF USING BUTYRIC ACID OR BUTYRIC ACID DERIVATIVES TO PROTECT AGAINST HAIR LOSS | Ansan Pharmaceuticals, Inc. (US) | 2000-06-14 | — | — | EP | claimed |
| EP-0793488-A4 | — | — | 1997-09-10 | — | — | EP | claimed |
| EP-0793488-A1 | INCREASING FETAL HEMOGLOBIN LEVELS USING CARBOXYLIC ESTERS | Rephaeli, Ada (US) | 1997-09-10 | — | — | EP | claimed |
| WO-1995024189-A1 | INCREASING FETAL HEMOGLOBIN LEVELS USING CARBOXYLIC ESTERS | REPHAELI ADA (US) | 1995-09-14 | — | — | WO | claimed |
| US-5962523-A | Methods of using butyric acid derivatives to protect against hair loss | DISCOVERY LABORATORIES, INC. (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0793488-A4 | — | — | 1997-09-10 | — | — | EP | disclosed |
| EP-0793488-A1 | INCREASING FETAL HEMOGLOBIN LEVELS USING CARBOXYLIC ESTERS | Rephaeli, Ada (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5569675-A | ADMINISTERING TO TREAT BLOOD DISORDERS | BAR ILAN UNIVERSITY (IL) | 1996-10-29 | — | — | US | disclosed |
| WO-1995024189-A1 | INCREASING FETAL HEMOGLOBIN LEVELS USING CARBOXYLIC ESTERS | REPHAELI ADA (US) | 1995-09-14 | — | — | WO | disclosed |
| EP-0302349-B1 | BIOLOGICALLY ACTIVE CARBOXYLIC ACID ESTERS | UNIV BAR ILAN (IL) | 1993-09-29 | — | — | EP | disclosed |
| US-5200553-A | Antitumor, immune response agents | KUPAT HOLIM HEALTH INSURANCE INSTITUTION OF THE GENERAL FEDERATION OF LABOR (IL) | 1993-04-06 | — | — | US | disclosed |
| EP-0302349-A2 | Biologically active carboxylic acid esters | BAR ILAN UNIVERSITY (IL) | 1989-02-08 | — | — | EP | disclosed |
| US-4599445-A | Process for benzophenone tetracarboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1986-07-08 | — | — | US | disclosed |
| US-4562271-A | Preparation of 3-alkanoyloxyphthalides | THE UPJOHN COMPANY (US) | 1985-12-31 | — | — | US | disclosed |
| US-4485247-A | 3-Alkanoyloxyphthalides | THE UPJOHN COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| EP-0125342-A1 | Process for preparation of aromatic polycarboxylic acids and intermediates therefor | THE UPJOHN COMPANY (US) | 1984-11-21 | — | — | EP | disclosed |