Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659627 | 0.76 | FOLH1 (0.38) | FOLH1 | |
| SCHEMBL1201695 | 0.75 | FOLH1 (0.45) | FOLH1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28645472 | 0.74 | FOLH1 (0.42) | FOLH1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3658802 | 0.69 | FOLH1 (0.43) | FOLH1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15111471 | 0.68 | THRB (0.39) | — | |
| SCHEMBL1202809 | 0.66 | RAB9A (0.42) | FOLH1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9071870 | 0.66 | AKR1C3 (0.34) | — | |
| SCHEMBL16467150 | 0.64 | TSHR (0.36) | — | |
| SCHEMBL25171764 | 0.64 | TTR (0.62) | — | |
| SCHEMBL1278397 | 0.64 | LMNA (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234954-B1 | TETRASUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS INC (US) | 2015-02-18 | — | — | EP | disclosed |