Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743600 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRGAA | |
| SCHEMBL28743602 | 0.82 | NAAA (0.45) | ALDH1A1TSHRDGKAGAA | |
| SCHEMBL28743298 | 0.81 | NAAA (0.51) | ALDH1A1TSHRDGKAGAA | |
| SCHEMBL12662617 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRDGKA | |
| SCHEMBL8744187 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRDGKA | |
| SCHEMBL8744185 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRDGKA | |
| SCHEMBL28743364 | 0.80 | NAAA (0.54) | ALDH1A1TSHRDGKA | |
| SCHEMBL11822034 | 0.78 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL11822041 | 0.78 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL1646209 | 0.77 | CACNA1B (0.38) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2837629-B1 | METHOD FOR SYNTHESIZING SAPROPTERIN DIHYDROCHLORIDE | ASYMCHEM LABORATORIES (TIANJIN) CO LTD (CN) | 2017-03-22 | — | — | EP | disclosed |
| EP-2837629-A1 | METHOD FOR SYNTHESIZING SAPROPTERIN DIHYDROCHLORIDE | Asymchem Laboratories (Tianjin) Co., Ltd (CN) | 2015-02-18 | — | — | EP | disclosed |