Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1633685 | 0.94 | KIF11 (0.53) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1635914 | 0.92 | HDAC3 (0.53) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| Phosphine SCHEMBL29270354 | 0.92 | KIF11 (0.52) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| Bromide SCHEMBL9938231 | 0.90 | KIF11 (0.50) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30806221 | 0.89 | KIF11 (0.46) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5329346 | 0.87 | KIF11 (0.53) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7708780 | 0.85 | KIF11 (0.66) | KIF11KCNH2 | |
| SCHEMBL27884300 | 0.82 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11754754 | 0.80 | CYP2C19 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL523363 | 0.80 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567605-A | Method and reagent for detecting protein lysine-3-hydroxybutyrylation | 杭州景杰生物科技股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| US-11385240-B2 | Reagents and methods for detecting protein lysine 3-hydroxybutyrylation | PTM BIO LLC (US) | 2022-07-12 | — | — | US | disclosed |
| US-20190331695-A1 | REAGENTS AND METHODS FOR DETECTING PROTEIN LYSINE 3-HYDROXYBUTYRYLATION | PTM BIO LLC (US) | 2019-10-31 | — | — | US | disclosed |
| CN-104592379-A | Method and reagent for detecting protein lysine-3-hydroxybutyrylation | JINGJIE PTM BIOLAB HANGZHOU CO LTD | 2015-05-06 | — | — | CN | disclosed |
| US-20150051093-A1 | Reagents And Methods for Detecting Protein Lysine 3-Hydroxybutyrylation | PTM BIOLABS, INC. (US) | 2015-02-19 | — | — | US | disclosed |