Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19809495 | 0.94 | KIF11 (0.62) | KIF11KCNH2PDE4BNPC1RAB9A | |
| SCHEMBL16468009 | 0.85 | KIF11 (0.55) | KIF11KCNH2 | |
| SCHEMBL22150730 | 0.83 | KIF11 (0.71) | KIF11KCNH2HTT | |
| SCHEMBL7708779 | 0.81 | KIF11 (0.69) | KIF11KCNH2HTT | |
| SCHEMBL7706703 | 0.81 | KIF11 (0.73) | KIF11KCNH2HTT | |
| SCHEMBL10877618 | 0.81 | KIF11 (0.73) | KIF11KCNH2HTT | |
| SCHEMBL1633685 | 0.80 | KIF11 (0.53) | KIF11NPSR1 | |
| SCHEMBL8972758 | 0.80 | KIF11 (0.68) | KIF11KCNH2HTT | |
| SCHEMBL15212059 | 0.80 | KIF11 (0.71) | KIF11KCNH2HTT | |
| SCHEMBL6834879 | 0.79 | PDE4B (0.54) | KIF11KCNH2PDE4BHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208234-A1 | POLY(ETHER-THIOETHER), POLY(ETHER-SULFOXIDE) AND POLY(ETHER-SULFONE) NUCLEIC ACIDS | BIO-RAD LABORATORIES, INC. (US) | 2002-05-29 | — | — | EP | disclosed |
| US-6348583-B1 | NUCLEOBASE CONTAINING POLYTHIOETHERS SYNTHESIZED ON POLYETHYLENE GLYCOL, SUCCINIC ANHYDRIDE AND PROPYLAMINE MODIFIED GLASS; NUCLEIC ACID MIMETICS | BIO-RAD LABORATORIES, INC. | 2002-02-19 | — | — | US | disclosed |
| WO-2001016365-A1 | POLY(ETHER-THIOETHER), POLY(ETHER-SULFOXIDE) AND POLY(ETHER-SULFONE) NUCLEIC ACIDS | BIO-RAD LABORATORIES, INC. (US) | 2001-03-08 | — | — | WO | disclosed |