⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10825603 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL8300133 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL4111613 | 0.79 | — | — | |
| SCHEMBL4111608 | 0.79 | — | — | |
| SCHEMBL3388819 | 0.78 | TGFBR1 (0.44) | — | |
| SCHEMBL125983 | 0.77 | — | — | |
| SCHEMBL10816655 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL2920884 | 0.76 | — | — | |
| SCHEMBL4044697 | 0.76 | — | — | |
| SCHEMBL11273625 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116285915-B | Environment-friendly high-temperature-resistant drilling fluid for shale deep well and preparation method thereof | 中石化石油工程技术服务有限公司 | 2024-04-09 | — | — | CN | claimed |
| WO-2023209569-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | WO | claimed |
| WO-2023209631-A1 | METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | WO | claimed |
| WO-2023209570-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | WO | claimed |
| CN-116285915-A | Environment-friendly high-temperature-resistant drilling fluid for shale deep well and preparation method thereof | 中石化石油工程技术服务有限公司 | 2023-06-23 | — | — | CN | claimed |
| EP-4189469-A1 | CONTACT LENSES WITH SOFTER LENS SURFACES | Alcon Inc. (CH) | 2023-06-07 | — | — | EP | claimed |
| EP-4121802-A1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | Alcon Inc. (CH) | 2023-01-25 | — | — | EP | claimed |
| EP-4121801-A1 | INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX | Alcon Inc. (CH) | 2023-01-25 | — | — | EP | claimed |
| EP-4121803-A1 | EMBEDDED SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2023-01-25 | — | — | EP | claimed |
| EP-4017346-A1 | CONTACT LENSES WITH SURFACES HAVING DIFFERENT SOFTNESS | Alcon Inc. (CH) | 2022-06-29 | — | — | EP | claimed |
| CN-109689714-A | Silicone hydrogels comprising N-alkylmethacrylamides and contact lenses made therefrom | 庄臣及庄臣视力保护公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109073783-A | Manufacture the method with the silicone hydrogel contact lenses of reduced evaporation rate | 库柏维景国际控股公司 | 2018-12-21 | — | — | CN | claimed |
| WO-2018009312-A1 | SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2018-01-11 | — | — | WO | claimed |
| CN-106459309-A | Silicone acrylamide copolymers | 庄臣及庄臣视力保护公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106459308-A | Silicone acrylamide copolymers | 庄臣及庄臣视力保护公司 | 2017-02-22 | — | — | CN | claimed |
| CN-103502317-B | Macroinitiators containing hydrophobic segments | 庄臣及庄臣视力保护公司 | 2017-02-08 | — | — | CN | claimed |
| EP-1077683-B1 | ANTIDEPRESSANT THERAPY | ALZA CORP (US) | 2002-12-11 | — | — | EP | claimed |
| US-20010055614-A1 | Antidepressant therapy | SEROFF SYLVIA (US) | 2001-12-27 | — | — | US | claimed |
| EP-1077683-A1 | ANTIDEPRESSANT THERAPY | ALZA CORPORATION (US) | 2001-02-28 | — | — | EP | claimed |
| WO-1999058115-A1 | ANTIDEPRESSANT THERAPY | ALZA CORPORATION (US) | 1999-11-18 | — | — | WO | claimed |