Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methallibure SCHEMBL393014 | 0.80 | GAA (0.31) | GAA | |
| Methallibure SCHEMBL4312430 | 0.78 | GAA (0.30) | GAA | |
| SCHEMBL6947071 | 0.78 | ALDH1A1 (0.40) | ALDH1A1GAATSHR | |
| SCHEMBL1770104 | 0.77 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4EMEN1MAPT | |
| SCHEMBL164682 | 0.77 | — | — | |
| SCHEMBL21239911 | 0.75 | — | — | |
| SCHEMBL3799164 | 0.73 | — | — | |
| SCHEMBL10815551 | 0.71 | — | — | |
| SCHEMBL10825603 | 0.69 | TSHR (0.44) | ALDH1A1GAAMEN1KMT2ATSHR | |
| Methallibure SCHEMBL6614118 | 0.69 | ATM (0.45) | ALDH1A1GAAKDM4EMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4697020-A | Derivatives of 2,4-thiazolidinedione | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |