SCHEMBL16468415

SCHEMBL16468415

CC(C)C[C@@H]([C]=O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCCN

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 8/20 0.51
KISS1R Q969F8 1/20 0.50
NPBWR1 P48145 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2183858 0.90 IL1RN (0.52) KISS1RNPBWR1
SCHEMBL2194704 0.86 IL1RN (0.55) KISS1RNPBWR1
SCHEMBL10750299 0.84 CTSC (0.54) GHSR
SCHEMBL31177131 0.84 NPBWR1 (0.60) GHSRNPBWR1
SCHEMBL31177122 0.84 NPBWR1 (0.60) GHSRNPBWR1
SCHEMBL29723828 0.84 NPBWR1 (0.60) GHSRNPBWR1
SCHEMBL2197039 0.84 ERAP2 (0.61) GHSR
SCHEMBL9114372 0.83 GHSR (0.54) GHSR
SCHEMBL31720495 0.83 ERAP2 (0.63) GHSR
SCHEMBL29750479 0.82 GHSR (0.59) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9173951-B2 Carbohydrate-based drug delivery polymers and conjugates thereof NEKTAR THERAPEUTICS (US) 2015-11-03 US disclosed
US-20150051371-A1 CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF NEKTAR THERAPEUTICS (US) 2015-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051371-A1 CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF STT3B, STT3A, DDOST GHSR 1832/4885KISS1R 3907/4885NPBWR1 1099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.