Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 7/20 | 0.41 |
| ▸ | SLC2A4 | P14672 | 3/20 | 0.39 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16468138 | 0.93 | SLC2A1 (0.41) | SLC2A1SLC2A4SLC2A8KDM4EALDH1A1 | |
| SCHEMBL16468158 | 0.91 | F2 (0.43) | TSHRNPC1KDM4EALDH1A1LMNA | |
| SCHEMBL16468257 | 0.88 | LPAR1 (0.47) | L3MBTL1TSHRSLC2A1SLC2A4SLC2A8 | |
| SCHEMBL16468164 | 0.87 | F2 (0.43) | L3MBTL1SLC2A1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL16468156 | 0.87 | LPAR1 (0.45) | L3MBTL1TSHRSLC2A1SLC2A4SLC2A8 | |
| SCHEMBL16468243 | 0.87 | CHRNB2 (0.47) | DRD2KDM4EALDH1A1PTGES | |
| SCHEMBL16467906 | 0.86 | LMNA (0.39) | L3MBTL1SMN1; SMN2KDM4ELMNAPTGES | |
| SCHEMBL15266143 | 0.85 | TSHR (0.52) | TSHRSLC2A1SLC2A4SLC2A8RAB9A | |
| SCHEMBL16467929 | 0.85 | KDM4E (0.48) | SLC2A1KDM4EALDH1A1PKM | |
| SCHEMBL16468160 | 0.85 | KDM4E (0.39) | SLC2A1SLC2A4SLC2A8KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150051257-A1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | ADAMED SP. ZO.O (PL) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051257-A1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | AQP4, BCL6, STS | L3MBTL1 1649/4885TSHR 834/4885SLC2A1 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.