Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16468251 | 0.86 | HDAC1 (0.43) | HDAC1HDAC3HDAC2NCOR2PTGES | |
| SCHEMBL16468482 | 0.86 | L3MBTL1 (0.42) | LMNASMN1; SMN2MRGPRX4KDM4EPTGES | |
| SCHEMBL16468158 | 0.86 | F2 (0.43) | LMNAKDM4EHDAC1HDAC3HDAC2 | |
| SCHEMBL15264904 | 0.86 | LMNA (0.46) | LMNASMN1; SMN2MRGPRX4KDM4EPTGES | |
| SCHEMBL16468138 | 0.85 | SLC2A1 (0.41) | LMNAMRGPRX4KDM4EMTNR1AMTNR1B | |
| SCHEMBL16468182 | 0.85 | HTR1A (0.48) | LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL16468447 | 0.82 | DRD4 (0.40) | LMNAKDM4EHDAC1MAPT | |
| SCHEMBL16468164 | 0.82 | F2 (0.43) | SMN1; SMN2KDM4EHDAC1L3MBTL1MAPT | |
| SCHEMBL16468243 | 0.82 | CHRNB2 (0.47) | KDM4EHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL16467917 | 0.82 | MTNR1A (0.45) | LMNAHDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150051257-A1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | ADAMED SP. ZO.O (PL) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051257-A1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | AQP4, BCL6, STS | LMNA 3042/4885SMN1; SMN2 193/4885MRGPRX4 2577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.