Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555850 | 1.00 | TSHR (0.48) | TSHRALDH1A1KDM4EL3MBTL1NR4A2 | |
| Dichlobenil SCHEMBL55606 | 0.83 | ALDH1A1 (0.55) | TSHRALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL1398115 | 0.83 | ALDH1A1 (0.43) | TSHRALDH1A1KDM4EL3MBTL1GAA | |
| Dichlobenil SCHEMBL1701380 | 0.83 | ALDH1A1 (0.55) | TSHRALDH1A1KDM4EL3MBTL1GAA | |
| Dichlobenil SCHEMBL28232070 | 0.80 | ALDH1A1 (0.53) | TSHRALDH1A1KDM4EL3MBTL1GAA | |
| Dichlobenil SCHEMBL10737856 | 0.80 | ALDH1A1 (0.53) | TSHRALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL28027128 | 0.79 | TSHR (0.50) | TSHRALDH1A1KDM4EL3MBTL1NR4A2 | |
| Dichlobenil SCHEMBL10741379 | 0.78 | ALDH1A1 (0.52) | TSHRALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL9129444 | 0.78 | CYP1A2 (0.57) | TSHRALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL6149211 | 0.77 | TSHR (0.48) | TSHRALDH1A1KDM4ENR4A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3813532-B1 | PROCESS FOR THE PREPARATION OF QUINMERAC | ADAMA AGAN LTD (IL) | 2024-02-28 | — | — | EP | claimed |
| CN-112423589-B | Process for preparing chloroquinolinic acid | 安道麦阿甘有限公司 | 2023-03-10 | — | — | CN | claimed |
| US-11427545-B2 | Process for the preparation of Quinmerac | ADAMA AGAN LTD. (IL) | 2022-08-30 | — | — | US | claimed |
| CN-111668481-B | Preparation method of metal aluminum secondary battery with multi-group organic micromolecules as positive electrode | 北京科技大学 | 2021-12-03 | — | — | CN | claimed |
| US-20210147362-A1 | PROCESS FOR THE PREPARATION OF QUINMERAC | ADAMA AGAN LTD. (IL) | 2021-05-20 | — | — | US | claimed |
| EP-3813532-A1 | PROCESS FOR THE PREPARATION OF QUINMERAC | Adama Agan Ltd. (IL) | 2021-05-05 | — | — | EP | claimed |
| CN-112423589-A | Process for preparing chloroquinolinic acid | 安道麦阿甘有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-111668481-A | Preparation method of metal aluminum secondary battery with multi-group organic micromolecules as positive electrode | 北京科技大学 | 2020-09-15 | — | — | CN | claimed |
| EP-2671575-A1 | Ras inhibitors | Universität Regensburg (DE) | 2013-12-11 | — | — | EP | claimed |
| WO-2025224262-A1 | COMBINATION THERAPIES COMPRISING A CDK2 DEGRADER AND A CDK4/6 INHIBITOR | MONTE ROSA THERAPEUTICS AG (CH) | 2025-10-30 | — | — | WO | disclosed |
| WO-2025224249-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS AG (CH) | 2025-10-30 | — | — | WO | disclosed |
| EP-4608816-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | Monte Rosa Therapeutics AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| US-20250263395-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS AG (CH) | 2025-08-21 | — | — | US | disclosed |
| US-20250114466-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2025-04-10 | — | — | US | disclosed |
| CN-1032440-A | The 4-aminopyridine derivatives class | PFIZER (US) | 1989-04-19 | — | — | CN | disclosed |
| EP-0311303-A2 | 4-aminopyridine derivatives | PFIZER INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| WO-1989002740-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | disclosed |
| EP-0006999-B1 | A PROCESS FOR THE PRODUCTION OF 2-CHLOROBENZONITRILE DERIVATIVES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-04-01 | — | — | EP | disclosed |
| US-4225534-A | FROM CHLORINATED 2-NITROBENZONITRILES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-09-30 | — | — | US | disclosed |
| EP-0006999-A1 | A process for the production of 2-chlorobenzonitrile derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250114466-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | DHFR, FOLR1, MTHFD2 | TSHR 1590/4885ALDH1A1 1219/4885KDM4E 2050/4885 |
| US-11427545-B2 | Process for the preparation of Quinmerac | NQO2, QARS1, P2RY11 | TSHR 4630/4885ALDH1A1 3338/4885KDM4E 2701/4885 |
| US-20210147362-A1 | PROCESS FOR THE PREPARATION OF QUINMERAC | NQO2, QARS1, P2RY11 | TSHR 4630/4885ALDH1A1 3338/4885KDM4E 2701/4885 |
| US-20250263395-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | CDK2, SKP2, CDK1 | TSHR 3902/4885ALDH1A1 3818/4885KDM4E 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.