Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | EDNRA | P25101 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647185 | 0.80 | LMNA (0.46) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL14009908 | 0.79 | ACP1 (0.61) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL28780801 | 0.79 | LMNA (0.57) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL2912774 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL2591215 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL27804813 | 0.78 | ACP1 (0.59) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL11979598 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL8088783 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL8796963 | 0.75 | ALDH1A1 (0.49) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL12801174 | 0.75 | ALDH1A1 (0.49) | ALDH1A1LMNAKDM4ECYP2C9EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11170444-A | — | — | None | — | — | JP | disclosed |
| JP-11012107-A | — | — | None | — | — | JP | disclosed |
| JP-9227316-A | — | — | None | — | — | JP | disclosed |
| CN-114730646-B | Conductive particle, method for producing same, and conductive material containing conductive particle | 日本化学工业株式会社 | 2024-03-19 | — | — | CN | disclosed |
| US-8299021-B2 | Macrocyclic inhibitors of hepatitis C virus replication | INTERMUNE, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-8299021-B2 | Macrocyclic inhibitors of hepatitis C virus replication | INTERMUNE, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-8299021-B2 | Macrocyclic inhibitors of hepatitis C virus replication | INTERMUNE, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-20120208995-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | ARRAY BIOPHARMA, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-20120208995-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | ARRAY BIOPHARMA, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-20120208995-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | ARRAY BIOPHARMA, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| EP-1749007-A2 | MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION | Intermune, Inc. (US) | 2007-02-07 | — | — | EP | disclosed |
| US-20050267018-A1 | Macrocyclic compounds as inhibitors of viral replication | HOFFMANN-LA ROCHE INC. | 2005-12-01 | — | — | US | disclosed |
| WO-2005095403-A2 | MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. (US) | 2005-10-13 | — | — | WO | disclosed |
| US-20040251164-A1 | Atmosphere improving tape for package package with atmosphere improving tape and method of manufacturing the package package container with atmosphere improving tape engaging device an package with engaging device | IDEMITSU UNITECH CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1462383-A1 | ATMOSPHERE IMPROVING TAPE FOR PACKAGE, PACKAGE WITH ATMOSPHERE IMPROVING TAPE AND METHOD OF MANUFACTURING THE PACKAGE, PACKAGE CONTAINER WITH ATMOSPHERE IMPROVING TAPE, ENGAGING DEVICE, AND PACKAGE WITH ENGAGING DEVICE | Idemitsu Unitech Co., Ltd. (JP) | 2004-09-29 | — | — | EP | disclosed |
| JP-2002167551-A | COATING MATERIAL COMPOSITION AND ITS MANUFACTURING METHOD | MIZU:KK | 2002-06-11 | — | — | JP | disclosed |
| JP-H11170444-A | PACKAGING BODY | TRY COMPANY:KK | 1999-06-29 | — | — | JP | disclosed |
| JP-H1112107-A | MICROORGANISM REMOVING AGENT FOR WATER TREATMENT AND BATHING AGENT CONTAINING MICROORGANISM REMOVING AGENT | SUZUKI YUSHI KOGYO KK | 1999-01-19 | — | — | JP | disclosed |
| EP-0888712-A1 | Laminate having anti-bacterial and mildewproofing actions | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |
| JP-H09227316-A | ANTIFUNGAL COMPOSITION | MATSUSHITA ELECTRIC WORKS LTD | 1997-09-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208995-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | EIF2AK2, HAVCR2, HCCS | ALDH1A1 2539/4885LMNA 1955/4885KDM4E 667/4885 |
| US-20050267018-A1 | Macrocyclic compounds as inhibitors of viral replication | EIF2AK2, HAVCR2, ZC3HAV1 | ALDH1A1 2109/4885LMNA 625/4885KDM4E 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.