Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 8/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213928 | 0.84 | DHODH (0.56) | MKNK1MKNK2HDAC4DHODHPOLB | |
| SCHEMBL16291436 | 0.82 | HDAC4 (0.48) | MKNK1MKNK2HDAC4DHODHL3MBTL1 | |
| SCHEMBL15997961 | 0.78 | ALDH1A1 (0.49) | HDAC4DHODHPOLBMAPTTSHR | |
| SCHEMBL19048355 | 0.78 | HDAC4 (0.47) | MKNK1MKNK2HDAC4DHODHPOLB | |
| SCHEMBL931676 | 0.77 | F7 (0.46) | MKNK1MKNK2CHEK2F7F3 | |
| SCHEMBL4927431 | 0.76 | CHEK2 (0.67) | MKNK1MKNK2DHODHMAP4K4CHEK2 | |
| SCHEMBL27613082 | 0.75 | HDAC4 (0.41) | HDAC4DHODHPOLBMAPTHSD17B10 | |
| SCHEMBL8467926 | 0.75 | HDAC4 (0.46) | HDAC4DHODHCYP3A4MAPTTSHR | |
| SCHEMBL8138043 | 0.75 | MAPT (0.56) | MKNK1MKNK2HDAC4DHODHPOLB | |
| SCHEMBL1124106 | 0.73 | WNT3A (0.46) | HDAC4DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119497709-A | Pyrimidine derivatives | ASKA 制药株式会社 | 2025-02-21 | — | — | CN | disclosed |
| WO-2011038572-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-04-07 | — | — | WO | disclosed |