Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458062 | 0.80 | GABRA1 (0.52) | HDAC4DHODHKMT2AMEN1ALDH1A1 | |
| SCHEMBL29959678 | 0.79 | RAB9A (0.50) | HDAC4DHODHKMT2AMEN1TP53 | |
| SCHEMBL121970 | 0.79 | RAB9A (0.50) | HDAC4DHODHKMT2AMEN1TP53 | |
| SCHEMBL3458918 | 0.78 | NPY5R (0.47) | HDAC4DHODHKMT2AMEN1ALDH1A1 | |
| SCHEMBL16780594 | 0.78 | HDAC4 (0.46) | HDAC4DHODHKMT2AMEN1ALDH1A1 | |
| SCHEMBL6850684 | 0.78 | SLC6A2 (0.49) | HDAC4DHODHKMT2AMEN1ALDH1A1 | |
| SCHEMBL8138043 | 0.78 | MAPT (0.56) | HDAC4DHODHKMT2AMEN1ALDH1A1 | |
| SCHEMBL218007 | 0.78 | L3MBTL1 (0.49) | HDAC4DHODHALDH1A1MAPTHPGD | |
| SCHEMBL30661704 | 0.78 | SLC6A2 (0.49) | HDAC4DHODHKMT2AMEN1ALDH1A1 | |
| SCHEMBL30661720 | 0.78 | L3MBTL1 (0.49) | HDAC4DHODHALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115943190-A | Multifunctional material for temporary bonding | 布鲁尔科技公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115461471-A | Chip surface connector and preparation method and application thereof | 南京金斯瑞生物科技有限公司 | 2022-12-09 | — | — | CN | claimed |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2026-03-31 | — | — | US | disclosed |
| US-12559495-B2 | Purine diones as Wnt pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2026-02-24 | — | — | US | disclosed |
| EP-4559908-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | S2CBio Inc. (KR) | 2025-05-28 | — | — | EP | disclosed |
| CN-113727972-B | Novel hydrazone derivatives having terminal amine groups substituted with aryl or heteroaryl groups and use thereof | 韩国科学技术研究院 | 2024-12-27 | — | — | CN | disclosed |
| WO-2024058617-A1 | ANTIVIRAL USE OF HETEROARYL DERIVATIVE COMPOUND | 일동제약(주) | 2024-03-21 | — | — | WO | disclosed |
| WO-2024019541-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-25 | — | — | WO | disclosed |
| WO-2024019541-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-25 | — | — | WO | disclosed |
| US-20230174533-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-06-08 | — | — | US | disclosed |
| US-20230174533-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-06-08 | — | — | US | disclosed |
| US-20160090386-A1 | Purine Diones As Wnt Pathway Modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-03-31 | — | — | US | disclosed |
| US-20160090386-A1 | Purine Diones As Wnt Pathway Modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-03-31 | — | — | US | disclosed |
| US-20160090386-A1 | Purine Diones As Wnt Pathway Modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-03-31 | — | — | US | disclosed |
| WO-2015187094-A1 | PHTHALIMIDE DERIVATIVES AS MODULATORS OF WNT PATHWAY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-12-10 | — | — | WO | disclosed |
| WO-2015094119-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015094119-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015094118-A1 | MALEIMIDE DERIVATIVES AS MODULATORS OF WNT PATHWAY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-06-25 | — | — | WO | disclosed |
| US-5931168-A | Applicator for coloring hair or fibers and methods for making and using same | ABERCROMBIE TRACY HILL (US) | 1999-08-03 | — | — | US | disclosed |
| US-5845653-A | Applicator for coloring hair or fibers and methods for making and using same | ABERCROMBIE TRACY H (US) | 1998-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090386-A1 | Purine Diones As Wnt Pathway Modulators | WNT1, WNT3A, CTNNB1 | HDAC4 4418/4885DHODH 993/4885KMT2A 3504/4885 |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | ABL1, TH, CYP3A43 | HDAC4 1023/4885DHODH 618/4885KMT2A 1604/4885 |
| US-20230174533-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | WNT1, WNT3A, WNT3 | HDAC4 3952/4885DHODH 1350/4885KMT2A 3027/4885 |
| US-12559495-B2 | Purine diones as Wnt pathway modulators | WNT1, CTNND1, WNT3A | HDAC4 2352/4885DHODH 1308/4885KMT2A 2932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.