SCHEMBL16472803

SCHEMBL16472803

c1ccc2c(c1)oc1ccc(-c3cc4cc5oc6ccccc6c5cc4c4cc5sc6ccccc6c5cc34)cc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.36
ALDH1A1 P00352 5/20 0.36
HPGD P15428 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
AHR P35869 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ALOX5 P09917 2/20 0.35
GPR3 P46089 1/20 0.34
MAOA P21397 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
POLB P06746 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
CHEK2 O96017 1/20 0.32
CASP3 P42574 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14725764 0.96 MAPT (0.37) MAPTALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL16472926 0.96 MAPT (0.37) MAPTALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL16472939 0.95 MAPT (0.36) MAPTALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL21180586 0.93 MAPT (0.36) MAPTALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL14725740 0.91 AHR (0.37) MAPTALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL16472674 0.90 GPR84 (0.35) MAPTALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL15946241 0.89 MAPT (0.39) MAPTALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL16472888 0.88 GRM4 (0.32) MAPTALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL21180648 0.88 AHR (0.36) MAPTALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL21180663 0.87 PLA2G2A (0.38) MAPTALDH1A1HPGDSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9118021-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-25 US disclosed
US-9118021-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-25 US disclosed
US-20140103300-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-04-17 US disclosed
US-20140103300-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-04-17 US disclosed