Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16472926 | 0.91 | MAPT (0.37) | PLA2G2APLA2G4AMAPTALDH1A1HPGD | |
| SCHEMBL16472939 | 0.90 | MAPT (0.36) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL14725764 | 0.88 | MAPT (0.37) | PLA2G2APLA2G4AMAPTALDH1A1HPGD | |
| SCHEMBL16472803 | 0.87 | MAPT (0.36) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL15946241 | 0.86 | MAPT (0.39) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL21180586 | 0.85 | MAPT (0.36) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL21180656 | 0.84 | NPC1 (0.34) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL14725740 | 0.83 | AHR (0.37) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL16472933 | 0.83 | ALOX5 (0.38) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL16472916 | 0.83 | ALOX5 (0.38) | MAPTALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10361380-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-07-23 | — | — | US | disclosed |